Engineered TAL Effector modulators for the large-scale gain-of-function screening

Recent effective use of TAL Effectors (TALEs) has provided an important approach to the design and synthesis of sequence-specific DNA-binding proteins. However, it is still a challenging task to design and manufacture effective TALE modulators because of the limited knowledge of TALEā€“DNA interaction...

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Bibliographic Details
Main Authors: Zhang, Hanshuo, Li, Juan, Hou, Sha, Wang, Gancheng, Jiang, Mingjun, Sun, Changhong, Hu, Xiongbing, Zhuang, Fengfeng, Dai, Zhifei, Dai, Junbiao, Xi, Jianzhong Jeff
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132705/