A Simple Repeat Polymorphism in the MITF-M Promoter Is a Key Regulator of White Spotting in Dogs

A Simple Repeat Polymorphism in the MITF-M Promoter Is a Key Regulator of White Spotting in Dogs

The white spotting locus (S) in dogs is colocalized with the MITF (microphtalmia-associated transcription factor) gene. The phenotypic effects of the four S alleles range from solid colour (S) to extreme white spotting (sw). We have investigated four candidate mutations associated with the sw allele...

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Bibliographic Details
Main Authors: Baranowska Körberg, Izabella, Sundström, Elisabeth, Meadows, Jennifer R. S., Rosengren Pielberg, Gerli, Gustafson, Ulla, Hedhammar, Åke, Karlsson, Elinor K., Seddon, Jennifer, Söderberg, Arne, Vilà, Carles, Zhang, Xiaolan, Åkesson, Mikael, Lindblad-Toh, Kerstin, Andersson, Göran, Andersson, Leif
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130573/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130573/

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