Targeting Angiogenesis and Tumor Microenvironment in Metastatic Colorectal Cancer: Role of Aflibercept

In the last decades, we have progressively observed an improvement in therapeutic options for metastatic colorectal cancer (mCRC) treatment with a progressive prolongation of survival. mCRC prognosis still remains poor with low percentage of 5-year survival. Targeted agents have improved results obt...

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Bibliographic Details
Main Authors: Giordano, Guido, Febbraro, Antonio, Venditti, Michele, Campidoglio, Serena, Olivieri, Nunzio, Raieta, Katia, Parcesepe, Pietro, Imbriani, Giusy Carmen, Remo, Andrea, Pancione, Massimo
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130202/