Modelling Cochlear Mechanics
The cochlea plays a crucial role in mammal hearing. The basic function of the cochlea is to map sounds of different frequencies onto corresponding characteristic positions on the basilar membrane (BM). Sounds enter the fluid-filled cochlea and cause deflection of the BM due to pressure differences b...
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| Format: | Online |
| Language: | English |
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Hindawi Publishing Corporation
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130145/ |
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pubmed-41301452014-08-18 Modelling Cochlear Mechanics Ni, Guangjian Elliott, Stephen J. Ayat, Mohammad Teal, Paul D. Review Article The cochlea plays a crucial role in mammal hearing. The basic function of the cochlea is to map sounds of different frequencies onto corresponding characteristic positions on the basilar membrane (BM). Sounds enter the fluid-filled cochlea and cause deflection of the BM due to pressure differences between the cochlear fluid chambers. These deflections travel along the cochlea, increasing in amplitude, until a frequency-dependent characteristic position and then decay away rapidly. The hair cells can detect these deflections and encode them as neural signals. Modelling the mechanics of the cochlea is of help in interpreting experimental observations and also can provide predictions of the results of experiments that cannot currently be performed due to technical limitations. This paper focuses on reviewing the numerical modelling of the mechanical and electrical processes in the cochlea, which include fluid coupling, micromechanics, the cochlear amplifier, nonlinearity, and electrical coupling. Hindawi Publishing Corporation 2014 2014-07-23 /pmc/articles/PMC4130145/ /pubmed/25136555 http://dx.doi.org/10.1155/2014/150637 Text en Copyright © 2014 Guangjian Ni et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Ni, Guangjian Elliott, Stephen J. Ayat, Mohammad Teal, Paul D. |
| spellingShingle |
Ni, Guangjian Elliott, Stephen J. Ayat, Mohammad Teal, Paul D. Modelling Cochlear Mechanics |
| author_facet |
Ni, Guangjian Elliott, Stephen J. Ayat, Mohammad Teal, Paul D. |
| author_sort |
Ni, Guangjian |
| title |
Modelling Cochlear Mechanics |
| title_short |
Modelling Cochlear Mechanics |
| title_full |
Modelling Cochlear Mechanics |
| title_fullStr |
Modelling Cochlear Mechanics |
| title_full_unstemmed |
Modelling Cochlear Mechanics |
| title_sort |
modelling cochlear mechanics |
| description |
The cochlea plays a crucial role in mammal hearing. The basic function of the cochlea is to map sounds of different frequencies onto corresponding characteristic positions on the basilar membrane (BM). Sounds enter the fluid-filled cochlea and cause deflection of the BM due to pressure differences between the cochlear fluid chambers. These deflections travel along the cochlea, increasing in amplitude, until a frequency-dependent characteristic position and then decay away rapidly. The hair cells can detect these deflections and encode them as neural signals. Modelling the mechanics of the cochlea is of help in interpreting experimental observations and also can provide predictions of the results of experiments that cannot currently be performed due to technical limitations. This paper focuses on reviewing the numerical modelling of the mechanical and electrical processes in the cochlea, which include fluid coupling, micromechanics, the cochlear amplifier, nonlinearity, and electrical coupling. |
| publisher |
Hindawi Publishing Corporation |
| publishDate |
2014 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130145/ |
| _version_ |
1613123405314260992 |