Withaferin A-Caused Production of Intracellular Reactive Oxygen Species Modulates Apoptosis via PI3K/Akt and JNKinase in Rabbit Articular Chondrocytes

Withaferin A (WFA) is known as a constituent of Ayurvedic medicinal plant, Withania somnifera, and has been used for thousands of years. Although WFA has been used for the treatment of osteoarthritis (OA) and has a wide range of biochemical and pharmacologic activities, there are no findings suggest...

Full description

Bibliographic Details
Main Authors: Yu, Seon-Mi, Kim, Song-Ja
Format: Online
Language:English
Published: The Korean Academy of Medical Sciences 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129194/