Cytoplasmic nanojunctions between lysosomes and sarcoplasmic reticulum are required for specific calcium signaling
Herein we demonstrate how nanojunctions between lysosomes and sarcoplasmic reticulum (L-SR junctions) serve to couple lysosomal activation to regenerative, ryanodine receptor-mediated cellular Ca 2+ waves. In pulmonary artery smooth muscle cells (PASMCs) it has been proposed that nicotinic acid aden...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
F1000Research
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126599/ |