A Multiscale Agent-Based in silico Model of Liver Fibrosis Progression

Chronic hepatic inflammation involves a complex interplay of inflammatory and mechanical influences, ultimately manifesting in a characteristic histopathology of liver fibrosis. We created an agent-based model (ABM) of liver tissue in order to computationally examine the consequence of liver inflamm...

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Bibliographic Details
Main Authors: Dutta-Moscato, Joyeeta, Solovyev, Alexey, Mi, Qi, Nishikawa, Taichiro, Soto-Gutierrez, Alejandro, Fox, Ira J., Vodovotz, Yoram
Format: Online
Language:English
Published: Frontiers Media S.A. 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126446/