Analytical Utility of Mass Spectral Binning in Proteomic Experiments by SPectral Immonium Ion Detection (SPIID)*

Unambiguous identification of tandem mass spectra is a cornerstone in mass-spectrometry-based proteomics. As the study of post-translational modifications (PTMs) by means of shotgun proteomics progresses in depth and coverage, the ability to correctly identify PTM-bearing peptides is essential, incr...

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Bibliographic Details
Main Authors: Kelstrup, Christian D., Frese, Christian, Heck, Albert J. R., Olsen, Jesper V., Nielsen, Michael L.
Format: Online
Language:English
Published: The American Society for Biochemistry and Molecular Biology 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125726/