Loss of Cytotoxicity and Gain of Cytokine Production in Murine Tumor-Activated NK Cells

NK cells are able to form a functional memory suggesting that some NK cells are surviving the activation process. We hypothesized that NK cell activation causes the development of a distinct NK cell subset and studied the fate of murine post-activation NK cells. Activation was achieved by in vivo an...

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Bibliographic Details
Main Authors: Müller, Jürgen R., Waldmann, Thomas A., Dubois, Sigrid
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125151/