Retinoic Acid Activates Two Pathways Required for Meiosis in Mice

In all sexually reproducing organisms, cells of the germ line must transition from mitosis to meiosis. In mice, retinoic acid (RA), the extrinsic signal for meiotic initiation, activates transcription of Stra8, which is required for meiotic DNA replication and the subsequent processes of meiotic pro...

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Bibliographic Details
Main Authors: Koubova, Jana, Hu, Yueh-Chiang, Bhattacharyya, Tanmoy, Soh, Y. Q. Shirleen, Gill, Mark E., Goodheart, Mary L., Hogarth, Cathryn A., Griswold, Michael D., Page, David C.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125102/