RPRD1A and RPRD1B Are Human RNA Polymerase II C-Terminal Domain Scaffolds for Ser5 Dephosphorylation

RPRD1A and RPRD1B Are Human RNA Polymerase II C-Terminal Domain Scaffolds for Ser5 Dephosphorylation

The RNA polymerase II (RNAPII) carboxyl-terminal domain (CTD) heptapeptide repeats (Y1-S2-P3-T4-S5-P6-S7) undergo dynamic phosphorylation and dephosphorylation during the transcription cycle to recruit factors that regulate transcription, RNA processing and chromatin modification. We show here that...

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Bibliographic Details
Main Authors: Ni, Zuyao, Xu, Chao, Guo, Xinghua, Hunter, Gerald O., Kuznetsova, Olga V., Tempel, Wolfram, Marcon, Edyta, Zhong, Guoqing, Guo, Hongbo, Kuo, Wei-Hung William, Li, Joyce, Young, Peter, Olsen, Jonathan B., Wan, Cuihong, Loppnau, Peter, El Bakkouri, Majida, Senisterra, Guillermo A., He, Hao, Huang, Haiming, Sidhu, Sachdev S., Emili, Andrew, Murphy, Shona, Mosley, Amber L., Arrowsmith, Cheryl H., Min, Jinrong, Greenblatt, Jack F.
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124035/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124035/

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