Aliskiren-attenuated myocardium apoptosis via regulation of autophagy and connexin-43 in aged spontaneously hypertensive rats

There are controversies about the mechanism of myocardium apoptosis in hypertensive heart disease. The aim of this study was to investigate the relationship among autophagy, Cx43 and apoptosis in aged spontaneously hypertensive rats (SHRs) and establish whether Aliskiren is effective or not for the...

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Bibliographic Details
Main Authors: Zhang, Wenbin, Zhao, Gang, Hu, Xiaona, Wang, Min, Li, Hua, Ye, Yong, Du, Qijun, Yao, Jin, Bao, Zhijun, Hong, Wei, Fu, Guosheng, Ge, Junbo, Qiu, Zhaohui
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124010/