Repeated Nitrogen Dioxide Exposures and Eosinophilic Airway Inflammation in Asthmatics: A Randomized Crossover Study

Background: Nitrogen dioxide (NO2), a ubiquitous atmospheric pollutant, may enhance the asthmatic response to allergens through eosinophilic activation in the airways. However, the effect of NO2 on inflammation without allergen exposure is poorly studied.

Bibliographic Details
Main Authors: Ezratty, Véronique, Guillossou, Gaëlle, Neukirch, Catherine, Dehoux, Monique, Koscielny, Serge, Bonay, Marcel, Cabanes, Pierre-André, Samet, Jonathan M., Mure, Patrick, Ropert, Luc, Tokarek, Sandra, Lambrozo, Jacques, Aubier, Michel
Format: Online
Language:English
Published: NLM-Export 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123022/
Description
Summary:Background: Nitrogen dioxide (NO2), a ubiquitous atmospheric pollutant, may enhance the asthmatic response to allergens through eosinophilic activation in the airways. However, the effect of NO2 on inflammation without allergen exposure is poorly studied.