Profiling of Biomarkers for the Exposure of Polycyclic Aromatic Hydrocarbons: Lamin-A/C Isoform 3, Poly[ADP-ribose] Polymerase 1, and Mitochondria Copy Number Are Identified as Universal Biomarkers

Profiling of Biomarkers for the Exposure of Polycyclic Aromatic Hydrocarbons: Lamin-A/C Isoform 3, Poly[ADP-ribose] Polymerase 1, and Mitochondria Copy Number Are Identified as Universal Biomarkers

This study investigated the profiling of polycyclic aromatic hydrocarbon- (PAH-) induced genotoxicity in cell lines and zebrafish. Each type of cells displayed different proportionality of apoptosis. Mitochondrial DNA (mtDNA) copy number was dramatically elevated after 5-day treatment of fluoranthen...

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Bibliographic Details
Main Authors: Kim, Hwan-Young, Kim, Hye-Ran, Kang, Min-Gu, Trang, Nguyen Thi Dai, Baek, Hee-Jo, Moon, Jae-Dong, Shin, Jong-Hee, Suh, Soon-Pal, Ryang, Dong-Wook, Kook, Hoon, Shin, Myung-Geun
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121044/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121044/

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