Diverse matrix metalloproteinase functions regulate cancer amoeboid migration

Diverse matrix metalloproteinase functions regulate cancer amoeboid migration

Rounded-amoeboid cancer cells use actomyosin contractility driven by Rho-ROCK and JAK-STAT3 to migrate efficiently. It has been suggested that rounded-amoeboid cancer cells do not require matrix metalloproteinases (MMPs) to invade. Here we compare MMP levels in rounded-amoeboid and elongated-mesench...

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Bibliographic Details
Main Authors: Orgaz, Jose L., Pandya, Pahini, Dalmeida, Rimple, Karagiannis, Panagiotis, Sanchez-Laorden, Berta, Viros, Amaya, Albrengues, Jean, Nestle, Frank O., Ridley, Anne J., Gaggioli, Cedric, Marais, Richard, Karagiannis, Sophia N., Sanz-Moreno, Victoria
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118761/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118761/

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