Simple, standardized incorporation of genetic risk into non-genetic risk prediction tools for complex traits: coronary heart disease as an example
Purpose: Genetic risk assessment is becoming an important component of clinical decision-making. Genetic Risk Scores (GRSs) allow the composite assessment of genetic risk in complex traits. A technically and clinically pertinent question is how to most easily and effectively combine a GRS with an as...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Frontiers Media S.A.
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117937/ |