Plasmacytoid Dendritic Cells Suppress HIV-1 Replication but Contribute to HIV-1 Induced Immunopathogenesis in Humanized Mice

Plasmacytoid Dendritic Cells Suppress HIV-1 Replication but Contribute to HIV-1 Induced Immunopathogenesis in Humanized Mice

The role of plasmacytoid dendritic cells (pDC) in human immunodeficiency virus type 1 (HIV-1) infection and pathogenesis remains unclear. HIV-1 infection in the humanized mouse model leads to persistent HIV-1 infection and immunopathogenesis, including type I interferons (IFN-I) induction, immune-ac...

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Bibliographic Details
Main Authors: Li, Guangming, Cheng, Menglan, Nunoya, Jun-ichi, Cheng, Liang, Guo, Haitao, Yu, Haisheng, Liu, Yong-jun, Su, Lishan, Zhang, Liguo
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117636/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117636/

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