Snail regulates Nanog status during the epithelial–mesenchymal transition via the Smad1/Akt/GSK3β signaling pathway in non-small-cell lung cancer

The epithelial–mesenchymal transition (EMT), a crucial step in cancer metastasis, is important in transformed cancer cells with stem cell-like properties. In this study, we established a Snail-overexpressing cell model for non-small-cell lung cancer (NSCLC) and investigated its underlying mechanism....

Full description

Bibliographic Details
Main Authors: Liu, Chen-Wei, Li, Ching-Hao, Yi-Jen, Peng, Cheng, Yu-Wen, Chen, Huei-Wen, Liao, Po-Lin, Kang, Jaw-Jou, Yeng, Mao-Hsiung
Format: Online
Language:English
Published: Impact Journals LLC 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116528/