Low insulin-like growth factor-1 level predicts survival in humans with exceptional longevity

Low insulin-like growth factor-1 level predicts survival in humans with exceptional longevity

Attenuated growth hormone and insulin-like growth factor-1 (GH/IGF-1) signaling is associated with extended lifespan in several animal models. However, the effect of diminished GH/IGF-1 activity on survival in humans has not been confirmed. We tested the hypothesis that IGF-1 levels in nonagenarians...

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Bibliographic Details
Main Authors: Milman, Sofiya, Atzmon, Gil, Huffman, Derek M, Wan, Junxiang, Crandall, Jill P, Cohen, Pinchas, Barzilai, Nir
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116456/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116456/

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