HSP70-binding protein HSPBP1 regulates chaperone expression at a posttranslational level and is essential for spermatogenesis

HSP70-binding protein HSPBP1 regulates chaperone expression at a posttranslational level and is essential for spermatogenesis

The cochaperone HSPBP1 controls chaperone expression at a posttranslational level by inhibiting the ubiquitylation and proteasomal degradation of inducible HSP70 proteins. This ensures the survival of spermatocytes, which are—similar to tum...

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Bibliographic Details
Main Authors: Rogon, Christian, Ulbricht, Anna, Hesse, Michael, Alberti, Simon, Vijayaraj, Preethi, Best, Diana, Adams, Ian R., Magin, Thomas M., Fleischmann, Bernd K., Höhfeld, Jörg
Format: Online
Language:English
Published: The American Society for Cell Biology 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116300/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116300/

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