Incidence of Cyp51 A Key Mutations in Aspergillus fumigatus—A Study on Primary Clinical Samples of Immunocompromised Patients in the Period of 1995–2013

As the incidence of azole resistance in Aspergillus fumigatus is rising and the diagnosis of invasive aspergillosis (IA) in immunocompromised patients is rarely based on positive culture yield, we screened our Aspergillus DNA sample collection for the occurrence of azole resistance mediating cyp51 A...

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Bibliographic Details
Main Authors: Spiess, Birgit, Postina, Patricia, Reinwald, Mark, Cornely, Oliver A., Hamprecht, Axel, Hoenigl, Martin, Lass-Flörl, Cornelia, Rath, Peter-Michael, Steinmann, Jörg, Miethke, Thomas, Lauten, Melchior, Will, Silke, Merker, Natalia, Hofmann, Wolf-Karsten, Buchheidt, Dieter
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114486/