IRAK-M Deficiency Promotes the Development of Type 1 Diabetes in NOD Mice
Type 1 diabetes mellitus (T1DM) is an organ-specific autoimmune disease characterized by progressive destruction of insulin-secreting pancreatic β-cells. Both T-cell–mediated adaptive responses as well as innate immune processes are involved in pathogenesis. Interleukin-1 receptor–associated kinase...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
American Diabetes Association
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113073/ |