Bayesian approach to single-cell differential expression analysis

Single-cell data provides means to dissect the composition of complex tissues and specialized cellular environments. However, the analysis of such measurements is complicated by high levels of technical noise and intrinsic biological variability. We describe a probabilistic model of expression magni...

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Bibliographic Details
Main Authors: Kharchenko, Peter V., Silberstein, Lev, Scadden, David T.
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112276/