Three New Humulane Sesquiterpenes from Cultures of the Fungus Antrodiella albocinnamomea
Three new humulane-type sesquiterpenes, antrodols A–C (1–3), were isolated from cultures of the fungus Antrodiella albocinnamomea. Their structures were elucidated on the basis of extensive spectroscopic analysis. Antrodols A–C (1–3) are first examples of humulane-type sesquiterpenes isolated from c...
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| Format: | Online |
| Language: | English |
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Springer Berlin Heidelberg
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111878/ |
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pubmed-4111878 |
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pubmed-41118782014-07-30 Three New Humulane Sesquiterpenes from Cultures of the Fungus Antrodiella albocinnamomea Chen, Zi-Ming Fan, Qiong-Ying Yin, Xia Yang, Xiao-Yan Li, Zheng-Hui Feng, Tao Liu, Ji-Kai Original Article Three new humulane-type sesquiterpenes, antrodols A–C (1–3), were isolated from cultures of the fungus Antrodiella albocinnamomea. Their structures were elucidated on the basis of extensive spectroscopic analysis. Antrodols A–C (1–3) are first examples of humulane-type sesquiterpenes isolated from cultures of higher fungi, and antrodol A (1) was the first report of humulane-type sesquiterpene with a methyl rearranged at C-3. All compounds were evaluated in the enzyme inhibition assay against two protein-tyrosine phosphatases (PTPs): MEG2 and PTP1Bc. Springer Berlin Heidelberg 2014-07-17 /pmc/articles/PMC4111878/ /pubmed/25089238 http://dx.doi.org/10.1007/s13659-014-0032-4 Text en © The Author(s) 2014 This article is published under license to BioMed Central Ltd. Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Chen, Zi-Ming Fan, Qiong-Ying Yin, Xia Yang, Xiao-Yan Li, Zheng-Hui Feng, Tao Liu, Ji-Kai |
| spellingShingle |
Chen, Zi-Ming Fan, Qiong-Ying Yin, Xia Yang, Xiao-Yan Li, Zheng-Hui Feng, Tao Liu, Ji-Kai Three New Humulane Sesquiterpenes from Cultures of the Fungus Antrodiella albocinnamomea |
| author_facet |
Chen, Zi-Ming Fan, Qiong-Ying Yin, Xia Yang, Xiao-Yan Li, Zheng-Hui Feng, Tao Liu, Ji-Kai |
| author_sort |
Chen, Zi-Ming |
| title |
Three New Humulane Sesquiterpenes from Cultures of the Fungus Antrodiella albocinnamomea |
| title_short |
Three New Humulane Sesquiterpenes from Cultures of the Fungus Antrodiella albocinnamomea |
| title_full |
Three New Humulane Sesquiterpenes from Cultures of the Fungus Antrodiella albocinnamomea |
| title_fullStr |
Three New Humulane Sesquiterpenes from Cultures of the Fungus Antrodiella albocinnamomea |
| title_full_unstemmed |
Three New Humulane Sesquiterpenes from Cultures of the Fungus Antrodiella albocinnamomea |
| title_sort |
three new humulane sesquiterpenes from cultures of the fungus antrodiella albocinnamomea |
| description |
Three new humulane-type sesquiterpenes, antrodols A–C (1–3), were isolated from cultures of the fungus Antrodiella albocinnamomea. Their structures were elucidated on the basis of extensive spectroscopic analysis. Antrodols A–C (1–3) are first examples of humulane-type sesquiterpenes isolated from cultures of higher fungi, and antrodol A (1) was the first report of humulane-type sesquiterpene with a methyl rearranged at C-3. All compounds were evaluated in the enzyme inhibition assay against two protein-tyrosine phosphatases (PTPs): MEG2 and PTP1Bc. |
| publisher |
Springer Berlin Heidelberg |
| publishDate |
2014 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111878/ |
| _version_ |
1613118145388609536 |