Design, Synthesis and Pharmacological Evaluation of Novel Vanadium-Containing Complexes as Antidiabetic Agents

Based on the data about structure and antidiabetic activity of twenty seven vanadium and zinc coordination complexes collected from literature we developed QSAR models using the GUSAR program. These QSAR models were applied to 10 novel vanadium coordination complexes designed in silico in order to p...

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Bibliographic Details
Main Authors: Fedorova, Elena V., Buryakina, Anna V., Zakharov, Alexey V., Filimonov, Dmitry A., Lagunin, Alexey A., Poroikov, Vladimir V.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109918/