A dynamin 1-, dynamin 3- and clathrin-independent pathway of synaptic vesicle recycling mediated by bulk endocytosis

The exocytosis of synaptic vesicles (SVs) elicited by potent stimulation is rapidly compensated by bulk endocytosis of SV membranes leading to large endocytic vacuoles (‘bulk’ endosomes). Subsequently, these vacuoles disappear in parallel with the reappearance of new SVs. We have used synapses of dy...

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Bibliographic Details
Main Authors: Wu, Yumei, O'Toole, Eileen T, Girard, Martine, Ritter, Brigitte, Messa, Mirko, Liu, Xinran, McPherson, Peter S, Ferguson, Shawn M, De Camilli, Pietro
Format: Online
Language:English
Published: eLife Sciences Publications, Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107917/