Cotinine halts the advance of Alzheimer's disease-like pathology and associated depressive-like behavior in Tg6799 mice

Alzheimer's disease (AD) is associated with cognitive and non-cognitive symptoms for which there are currently no effective therapies. We have previously reported that cotinine, a natural product obtained from tobacco leaves, prevented memory loss and diminished amyloid-β (Aβ) plaque pathology...

Full description

Bibliographic Details
Main Authors: Patel, Sagar, Grizzell, J. Alex, Holmes, Rosalee, Zeitlin, Ross, Solomon, Rosalynn, Sutton, Thomas L., Rohani, Adeeb, Charry, Laura C., Iarkov, Alexandre, Mori, Takashi, Echeverria Moran, Valentina
Format: Online
Language:English
Published: Frontiers Media S.A. 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107855/