Acupuncture at Waiguan (TE5) influences activation/deactivation of functional brain areas in ischemic stroke patients and healthy people: A functional MRI study☆

Acupuncture at Waiguan (TE5) influences activation/deactivation of functional brain areas in ischemic stroke patients and healthy people: A functional MRI study☆

In the present study, 10 patients with ischemic stroke in the left hemisphere and six healthy controls were subjected to acupuncture at right Waiguan (TE5). In ischemic stroke subjects, functional MRI showed enhanced activation in Broadmann areas 5, 6, 7, 18, 19, 24, 32, the hypothalamic inferior lo...

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Main Authors: Chen, Junqi, Huang, Yong, Lai, Xinsheng, Tang, Chunzhi, Yang, Junjun, Chen, Hua, Zeng, Tongjun, Wu, Junxian, Qu, Shanshan
Format: Online
Language:English
Published: Medknow Publications & Media Pvt Ltd 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107521/
id pubmed-4107521
recordtype oai_dc
spelling pubmed-41075212014-09-09 Acupuncture at Waiguan (TE5) influences activation/deactivation of functional brain areas in ischemic stroke patients and healthy people: A functional MRI study☆ Chen, Junqi Huang, Yong Lai, Xinsheng Tang, Chunzhi Yang, Junjun Chen, Hua Zeng, Tongjun Wu, Junxian Qu, Shanshan Research and Report Article: Acupuncture and Moxibustion and Neural Regeneration In the present study, 10 patients with ischemic stroke in the left hemisphere and six healthy controls were subjected to acupuncture at right Waiguan (TE5). In ischemic stroke subjects, functional MRI showed enhanced activation in Broadmann areas 5, 6, 7, 18, 19, 24, 32, the hypothalamic inferior lobe, the mamillary body, and the ventral posterolateral nucleus of the left hemisphere, and Broadmann areas 4, 6, 7, 18, 19 and 32 of the right hemisphere, but attenuated activation of Broadmann area 13, the hypothalamic inferior lobe, the posterior lobe of the tonsil of cerebellum, and the culmen of the anterior lobe of hypophysis, in the left hemisphere and Broadmann area 13 in the right hemisphere. In ischemic stroke subjects, a number of deactivated brain areas were enhanced, including Broadmann areas 6, 11, 20, 22, 37, and 47, the culmen of the anterior lobe of hypophysis, alae lingulae cerebella, and the posterior lobe of the tonsil of cerebellum of the left hemisphere, and Broadmann areas 8, 37, 45 and 47, the culmen of the anterior lobe of hypophysis, pars tuberalis adenohypophyseos, inferior border of lentiform nucleus, lateral globus pallidus, inferior temporal gyrus, and the parahippocampal gyrus of the right hemisphere. These subjects also exhibited attenuation of a number of deactivated brain areas, including Broadmann area 7. These data suggest that acupuncture at Waiguan specifically alters brain function in regions associated with sensation, vision, and motion in ischemic stroke patients. By contrast, in normal individuals, acupuncture at Waiguan generally activates brain areas associated with insomnia and other functions. Medknow Publications & Media Pvt Ltd 2013-01-25 /pmc/articles/PMC4107521/ /pubmed/25206592 http://dx.doi.org/10.3969/j.issn.1673-5374.2013.03.004 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Chen, Junqi
Huang, Yong
Lai, Xinsheng
Tang, Chunzhi
Yang, Junjun
Chen, Hua
Zeng, Tongjun
Wu, Junxian
Qu, Shanshan
spellingShingle Chen, Junqi
Huang, Yong
Lai, Xinsheng
Tang, Chunzhi
Yang, Junjun
Chen, Hua
Zeng, Tongjun
Wu, Junxian
Qu, Shanshan
Acupuncture at Waiguan (TE5) influences activation/deactivation of functional brain areas in ischemic stroke patients and healthy people: A functional MRI study☆
author_facet Chen, Junqi
Huang, Yong
Lai, Xinsheng
Tang, Chunzhi
Yang, Junjun
Chen, Hua
Zeng, Tongjun
Wu, Junxian
Qu, Shanshan
author_sort Chen, Junqi
title Acupuncture at Waiguan (TE5) influences activation/deactivation of functional brain areas in ischemic stroke patients and healthy people: A functional MRI study☆
title_short Acupuncture at Waiguan (TE5) influences activation/deactivation of functional brain areas in ischemic stroke patients and healthy people: A functional MRI study☆
title_full Acupuncture at Waiguan (TE5) influences activation/deactivation of functional brain areas in ischemic stroke patients and healthy people: A functional MRI study☆
title_fullStr Acupuncture at Waiguan (TE5) influences activation/deactivation of functional brain areas in ischemic stroke patients and healthy people: A functional MRI study☆
title_full_unstemmed Acupuncture at Waiguan (TE5) influences activation/deactivation of functional brain areas in ischemic stroke patients and healthy people: A functional MRI study☆
title_sort acupuncture at waiguan (te5) influences activation/deactivation of functional brain areas in ischemic stroke patients and healthy people: a functional mri study☆
description In the present study, 10 patients with ischemic stroke in the left hemisphere and six healthy controls were subjected to acupuncture at right Waiguan (TE5). In ischemic stroke subjects, functional MRI showed enhanced activation in Broadmann areas 5, 6, 7, 18, 19, 24, 32, the hypothalamic inferior lobe, the mamillary body, and the ventral posterolateral nucleus of the left hemisphere, and Broadmann areas 4, 6, 7, 18, 19 and 32 of the right hemisphere, but attenuated activation of Broadmann area 13, the hypothalamic inferior lobe, the posterior lobe of the tonsil of cerebellum, and the culmen of the anterior lobe of hypophysis, in the left hemisphere and Broadmann area 13 in the right hemisphere. In ischemic stroke subjects, a number of deactivated brain areas were enhanced, including Broadmann areas 6, 11, 20, 22, 37, and 47, the culmen of the anterior lobe of hypophysis, alae lingulae cerebella, and the posterior lobe of the tonsil of cerebellum of the left hemisphere, and Broadmann areas 8, 37, 45 and 47, the culmen of the anterior lobe of hypophysis, pars tuberalis adenohypophyseos, inferior border of lentiform nucleus, lateral globus pallidus, inferior temporal gyrus, and the parahippocampal gyrus of the right hemisphere. These subjects also exhibited attenuation of a number of deactivated brain areas, including Broadmann area 7. These data suggest that acupuncture at Waiguan specifically alters brain function in regions associated with sensation, vision, and motion in ischemic stroke patients. By contrast, in normal individuals, acupuncture at Waiguan generally activates brain areas associated with insomnia and other functions.
publisher Medknow Publications & Media Pvt Ltd
publishDate 2013
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107521/
_version_ 1613116812117934080

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