Notch signaling deficiency underlies age-dependent depletion of satellite cells in muscular dystrophy
Duchenne muscular dystrophy (DMD) is a devastating disease characterized by muscle wasting, loss of mobility and death in early adulthood. Satellite cells are muscle-resident stem cells responsible for the repair and regeneration of damaged muscles. One pathological feature of DMD is the progressive...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Company of Biologists Limited
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107328/ |