Notch signaling deficiency underlies age-dependent depletion of satellite cells in muscular dystrophy

Duchenne muscular dystrophy (DMD) is a devastating disease characterized by muscle wasting, loss of mobility and death in early adulthood. Satellite cells are muscle-resident stem cells responsible for the repair and regeneration of damaged muscles. One pathological feature of DMD is the progressive...

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Bibliographic Details
Main Authors: Jiang, Chunhui, Wen, Yefei, Kuroda, Kazuki, Hannon, Kevin, Rudnicki, Michael A., Kuang, Shihuan
Format: Online
Language:English
Published: The Company of Biologists Limited 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107328/