Clostridium difficile in Children: To Treat or Not to Treat?

Clostridium difficile infection has been increasing since 2000 in children and in adults. Frequent antibiotics use, comorbidity, and the development of hypervirulent strains have increased the risk of infection. Despite the high carriage rates of C. difficile, infants rarely develop clinical infecti...

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Main Author: Shim, Jung Ok
Format: Online
Language:English
Published: The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107224/
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spelling pubmed-41072242014-07-24 Clostridium difficile in Children: To Treat or Not to Treat? Shim, Jung Ok Review Article Clostridium difficile infection has been increasing since 2000 in children and in adults. Frequent antibiotics use, comorbidity, and the development of hypervirulent strains have increased the risk of infection. Despite the high carriage rates of C. difficile, infants rarely develop clinical infection. Discontinuing antibiotics and supportive management usually leads to resolution of disease. Antibiotics use should be stratified depending on the patient's age and severity of the disease. The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition 2014-06 2014-06-30 /pmc/articles/PMC4107224/ /pubmed/25061582 http://dx.doi.org/10.5223/pghn.2014.17.2.80 Text en Copyright © 2014 by The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Shim, Jung Ok
spellingShingle Shim, Jung Ok
Clostridium difficile in Children: To Treat or Not to Treat?
author_facet Shim, Jung Ok
author_sort Shim, Jung Ok
title Clostridium difficile in Children: To Treat or Not to Treat?
title_short Clostridium difficile in Children: To Treat or Not to Treat?
title_full Clostridium difficile in Children: To Treat or Not to Treat?
title_fullStr Clostridium difficile in Children: To Treat or Not to Treat?
title_full_unstemmed Clostridium difficile in Children: To Treat or Not to Treat?
title_sort clostridium difficile in children: to treat or not to treat?
description Clostridium difficile infection has been increasing since 2000 in children and in adults. Frequent antibiotics use, comorbidity, and the development of hypervirulent strains have increased the risk of infection. Despite the high carriage rates of C. difficile, infants rarely develop clinical infection. Discontinuing antibiotics and supportive management usually leads to resolution of disease. Antibiotics use should be stratified depending on the patient's age and severity of the disease.
publisher The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition
publishDate 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107224/
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