Repair of Oxidative DNA Base Damage in the Host Genome Influences the HIV Integration Site Sequence Preference

Repair of Oxidative DNA Base Damage in the Host Genome Influences the HIV Integration Site Sequence Preference

Host base excision repair (BER) proteins that repair oxidative damage enhance HIV infection. These proteins include the oxidative DNA damage glycosylases 8-oxo-guanine DNA glycosylase (OGG1) and mutY homolog (MYH) as well as DNA polymerase beta (PolĪ²). While deletion of oxidative BER genes leads to...

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Bibliographic Details
Main Authors: Bennett, Geoffrey R., Peters, Ryan, Wang, Xiao-hong, Hanne, Jeungphill, Sobol, Robert W., Bundschuh, Ralf, Fishel, Richard, Yoder, Kristine E.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106905/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106905/

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