Carboxypeptidase E Modulates Intestinal Immune Homeostasis and Protects against Experimental Colitis in Mice

Enteroendocrine cells (EEC) produce neuropeptides, which are crucially involved in the maintenance of the intestinal barrier. Hence, EEC dysfunction is suggested to be involved in the complex pathophysiology of inflammatory bowel disease (IBD), which is characterized by decreased intestinal barrier...

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Bibliographic Details
Main Authors: Bär, Florian, Föh, Bandik, Pagel, René, Schröder, Torsten, Schlichting, Heidi, Hirose, Misa, Lemcke, Susanne, Klinger, Antje, König, Peter, Karsten, Christian M., Büning, Jürgen, Lehnert, Hendrik, Fellermann, Klaus, Ibrahim, Saleh M., Sina, Christian
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106776/