Therapeutic Targeting of c-Myc in T-Cell Acute Lymphoblastic Leukemia (T-ALL)

T-ALL patients treated with intensive chemotherapy achieve high rates of remission. However, frequent long-term toxicities and relapses into chemotherapy-refractory tumors constitute major clinical challenges which could be met by targeted therapies. c-MYC is a central oncogene in T-ALL, prompting t...

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Bibliographic Details
Main Authors: Loosveld, Marie, Castellano, Rémy, Gon, Stéphanie, Goubard, Armelle, Crouzet, Thomas, Pouyet, Laurent, Prebet, Thomas, Vey, Norbert, Nadel, Bertrand, Collette, Yves, Payet-Bornet, Dominique
Format: Online
Language:English
Published: Impact Journals LLC 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102800/