Therapeutic Targeting of c-Myc in T-Cell Acute Lymphoblastic Leukemia (T-ALL)
T-ALL patients treated with intensive chemotherapy achieve high rates of remission. However, frequent long-term toxicities and relapses into chemotherapy-refractory tumors constitute major clinical challenges which could be met by targeted therapies. c-MYC is a central oncogene in T-ALL, prompting t...
Main Authors: | , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Impact Journals LLC
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102800/ |