HIV-1 Capture and Transmission by Dendritic Cells: The Role of Viral Glycolipids and the Cellular Receptor Siglec-1

Dendritic cells (DCs) are essential in order to combat invading viruses and trigger antiviral responses. Paradoxically, in the case of HIV-1, DCs might contribute to viral pathogenesis through trans-infection, a mechanism that promotes viral capture and transmission to target cells, especially after...

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Bibliographic Details
Main Authors: Izquierdo-Useros, Nuria, Lorizate, Maier, McLaren, Paul J., Telenti, Amalio, Kräusslich, Hans-Georg, Martinez-Picado, Javier
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102576/