Recombinant Antigens Expressed in Pichia pastoris for the Diagnosis of Sleeping Sickness Caused by Trypanosoma brucei gambiense

Population screening for the chronic form of sleeping sickness or gambiense human African trypanosomiasis (HAT) is still based on an antibody detection test against the native variant surface glycoprotein (VSG) LiTat 1.3. This protein is produced through massive infections of lab animals with highly...

Full description

Bibliographic Details
Main Authors: Rogé, Stijn, Van Nieuwenhove, Liesbeth, Meul, Magali, Heykers, Annick, Brouwer de Koning, Annette, Bebronne, Nicolas, Guisez, Yves, Büscher, Philippe
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102443/