Signaling Domain of Sonic Hedgehog as Cannibalistic Calcium-Regulated Zinc-Peptidase
Sonic Hedgehog (Shh) is a representative of the evolutionary closely related class of Hedgehog proteins that have essential signaling functions in animal development. The N-terminal domain (ShhN) is also assigned to the group of LAS proteins (LAS = Lysostaphin type enzymes, D-Ala-D-Ala metalloprotea...
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102407/ |