The Role of Hypoxia Inducible Factor-1 in Hepatocellular Carcinoma

Hypoxia is a common feature of many solid tumors, including hepatocellular carcinoma (HCC). Hypoxia can promote tumor progression and induce radiation and chemotherapy resistance. As one of the major mediators of hypoxic response, hypoxia inducible factor-1 (HIF-1) has been shown to activate hypoxia...

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Bibliographic Details
Main Authors: Luo, Dongjun, Wang, Zhongxia, Wu, Junyi, Jiang, Chunping, Wu, Junhua
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101982/