Quantitative Proteomics to Characterize Specific Histone H2A Proteolysis in Chronic Lymphocytic Leukemia and the Myeloid THP-1 Cell Line

Proteome studies on hematological malignancies contribute to the understanding of the disease mechanism and to the identification of new biomarker candidates. With the isobaric tag for relative and absolute quantitation (iTRAQ) method we analyzed the protein expression between B-cells of healthy peo...

Full description

Bibliographic Details
Main Authors: Glibert, Pieter, Vossaert, Liesbeth, Van Steendam, Katleen, Lambrecht, Stijn, Van Nieuwerburgh, Filip, Offner, Fritz, Kipps, Thomas, Dhaenens, Maarten, Deforce, Dieter
Format: Online
Language:English
Published: MDPI 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100102/