Fitness Is Strongly Influenced by Rare Mutations of Large Effect in a Microbial Mutation Accumulation Experiment
Our understanding of the evolutionary consequences of mutation relies heavily on estimates of the rate and fitness effect of spontaneous mutations generated by mutation accumulation (MA) experiments. We performed a classic MA experiment in which frequent sampling of MA lines was combined with whole...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Genetics Society of America
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096375/ |