ALK5-dependent TGF-β signaling is a major determinant of late stage adult neurogenesis

The transforming growth factor-β (TGF-β) signaling pathway serves critical functions in central nervous system (CNS) development, but apart from its proposed neuroprotective actions, its physiological role in the adult brain is unclear. We observed a prominent activation of TGF-β signaling in the ad...

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Bibliographic Details
Main Authors: He, Yingbo, Zhang, Hui, Yung, Andrea, Villeda, Saul A, Jaeger, Philipp A, Olayiwola, Oluwatobi, Fainberg, Nina, Wyss-Coray, Tony
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096284/