Poxviral-based vaccine elicits immunologic responses in prostate cancer patients

Prostvac is a poxviral-based vaccine designed to target prostate-specific antigen (PSA) in prostate cancer patients. Recently, the potential toxicity and immunological impact of this immunotherapy were reviewed in the context of new clinical data. Our findings suggest that Prostvac is safe and elici...

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Main Authors: Madan, Ravi A, Heery, Christopher R, Gulley, James L
Format: Online
Language:English
Published: Landes Bioscience 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091323/
id pubmed-4091323
recordtype oai_dc
spelling pubmed-40913232014-08-05 Poxviral-based vaccine elicits immunologic responses in prostate cancer patients Madan, Ravi A Heery, Christopher R Gulley, James L Author's View Prostvac is a poxviral-based vaccine designed to target prostate-specific antigen (PSA) in prostate cancer patients. Recently, the potential toxicity and immunological impact of this immunotherapy were reviewed in the context of new clinical data. Our findings suggest that Prostvac is safe and elicits anticancer immune responses, both alone and in combinatorial approaches. Landes Bioscience 2014-04-29 /pmc/articles/PMC4091323/ /pubmed/25097802 http://dx.doi.org/10.4161/onci.28611 Text en Copyright © 2014 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Madan, Ravi A
Heery, Christopher R
Gulley, James L
spellingShingle Madan, Ravi A
Heery, Christopher R
Gulley, James L
Poxviral-based vaccine elicits immunologic responses in prostate cancer patients
author_facet Madan, Ravi A
Heery, Christopher R
Gulley, James L
author_sort Madan, Ravi A
title Poxviral-based vaccine elicits immunologic responses in prostate cancer patients
title_short Poxviral-based vaccine elicits immunologic responses in prostate cancer patients
title_full Poxviral-based vaccine elicits immunologic responses in prostate cancer patients
title_fullStr Poxviral-based vaccine elicits immunologic responses in prostate cancer patients
title_full_unstemmed Poxviral-based vaccine elicits immunologic responses in prostate cancer patients
title_sort poxviral-based vaccine elicits immunologic responses in prostate cancer patients
description Prostvac is a poxviral-based vaccine designed to target prostate-specific antigen (PSA) in prostate cancer patients. Recently, the potential toxicity and immunological impact of this immunotherapy were reviewed in the context of new clinical data. Our findings suggest that Prostvac is safe and elicits anticancer immune responses, both alone and in combinatorial approaches.
publisher Landes Bioscience
publishDate 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091323/
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