Structural basis of the heterodimerization of the MST and RASSF SARAH domains in the Hippo signalling pathway

The heterodimeric structure of the MST1 and RASSF5 SARAH domains is presented. A comparison of homodimeric and heterodimeric interactions provides a structural basis for the preferential association of the SARAH heterodimer.

Bibliographic Details
Main Authors: Hwang, Eunha, Cheong, Hae-Kap, Mushtaq, Ameeq Ul, Kim, Hye-Yeon, Yeo, Kwon Joo, Kim, Eunhee, Lee, Woo Cheol, Hwang, Kwang Yeon, Cheong, Chaejoon, Jeon, Young Ho
Format: Online
Language:English
Published: International Union of Crystallography 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089488/