State-Dependent Network Connectivity Determines Gating in a K+ Channel

X-ray crystallography has provided tremendous insight into the different structural states of membrane proteins and, in particular, of ion channels. However, the molecular forces that determine the thermodynamic stability of a particular state are poorly understood. Here we analyze the different X-r...

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Bibliographic Details
Main Authors: Bollepalli, Murali K., Fowler, Philip W., Rapedius, Markus, Shang, Lijun, Sansom, Mark S.P., Tucker, Stephen J., Baukrowitz, Thomas
Format: Online
Language:English
Published: Cell Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087272/