PTHGRN: unraveling post-translational hierarchical gene regulatory networks using PPI, ChIP-seq and gene expression data

PTHGRN: unraveling post-translational hierarchical gene regulatory networks using PPI, ChIP-seq and gene expression data

Interactions among transcriptional factors (TFs), cofactors and other proteins or enzymes can affect transcriptional regulatory capabilities of eukaryotic organisms. Post-translational modifications (PTMs) cooperate with TFs and epigenetic alterations to constitute a hierarchical complexity in trans...

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Bibliographic Details
Main Authors: Guan, Daogang, Shao, Jiaofang, Zhao, Zhongying, Wang, Panwen, Qin, Jing, Deng, Youping, Boheler, Kenneth R., Wang, Junwen, Yan, Bin
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086064/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086064/

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