Retroviral-infection increases tumorigenic potential of MDA-MB-231 breast carcinoma cells by expanding an aldehyde dehydrogenase (ALDH1) positive stem-cell like population

Retroviral-infection increases tumorigenic potential of MDA-MB-231 breast carcinoma cells by expanding an aldehyde dehydrogenase (ALDH1) positive stem-cell like population

Retroviral transformation has been associated with pro-proliferative oncogenic signaling in human cells. The current study demonstrates that transduction of human breast carcinoma cells (MDA-MB231) with LXSN and QCXIP retroviral vectors causes significant increases in growth rate, clonogenic fractio...

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Bibliographic Details
Main Authors: Wegman-Points, Lauren J., Teoh-Fitzgerald, Melissa L.T., Mao, Gaowei, Zhu, Yueming, Fath, Melissa A., Spitz, Douglas R., Domann, Frederick E.
Format: Online
Language:English
Published: Elsevier 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085353/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085353/

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