Novel gramicidin formulations in cationic lipid as broad-spectrum microbicidal agents

Dioctadecyldimethylammonium bromide (DODAB) is an antimicrobial lipid that can be dispersed as large closed bilayers (LV) or bilayer disks (BF). Gramicidin (Gr) is an antimicrobial peptide assembling as channels in membranes and increasing their permeability towards cations. In mammalian cells, DODA...

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Bibliographic Details
Main Authors: Ragioto, Danielle AMT, Carrasco, Letícia DM, Carmona-Ribeiro, Ana M
Format: Online
Language:English
Published: Dove Medical Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085336/