A clinician's guide to the assessment and interpretation of noninferiority trials for novel therapies
A noninferiority trial is designed to demonstrate that an experimental therapy is not worse than an active control. Although noninferiority trials are superficially similar to conventional superiority trials, there are fundamental differences. In particular, aspects of a study that make the therapie...
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| Format: | Online |
| Language: | English |
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Open Medicine Publications, Inc
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085087/ |