An Animal Model with a Cardiomyocyte-Specific Deletion of Estrogen Receptor Alpha: Functional, Metabolic, and Differential Network Analysis

Estrogen exerts diverse biological effects in multiple tissues in both animals and humans. Much of the accumulated knowledge on the role of estrogen receptor (ER) in the heart has been obtained from studies using ovariectomized mice, whole body ER gene knock-out animal models, ex vivo heart studies,...

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Bibliographic Details
Main Authors: Devanathan, Sriram, Whitehead, Timothy, Schweitzer, George G., Fettig, Nicole, Kovacs, Attila, Korach, Kenneth S., Finck, Brian N., Shoghi, Kooresh I.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085004/