Topical Herbal Application in the Management of Atopic Dermatitis: A Review of Animal Studies

Herbs are widely used in the treatment of atopic dermatitis (AD) in Eastern Asian countries, and certain herbs regarded have anti-inflammatory properties that can help with AD. With the goal of developing a topical herbal agent for AD, we conducted a systematic review of in vivo studies of AD-like s...

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Main Authors:	Yun, Younghee, Kim, Kyuseok, Choi, Inhwa, Ko, Seong-Gyu
Format:	Online
Language:	English
Published:	Hindawi Publishing Corporation 2014
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082915/

id	pubmed-4082915
recordtype	oai_dc
spelling	pubmed-40829152014-07-14 Topical Herbal Application in the Management of Atopic Dermatitis: A Review of Animal Studies Yun, Younghee Kim, Kyuseok Choi, Inhwa Ko, Seong-Gyu Review Article Herbs are widely used in the treatment of atopic dermatitis (AD) in Eastern Asian countries, and certain herbs regarded have anti-inflammatory properties that can help with AD. With the goal of developing a topical herbal agent for AD, we conducted a systematic review of in vivo studies of AD-like skin models for screening potential herbs. Searches were conducted from PubMed and EMBASE. After all, 22 studies were included for this review. We judged most of the domains of all studies to be at unclear risk of bias. Among 22 included studies, 21 herbs have been reported to reduce AD-like skin lesions in mouse models by suppressing Th2 cell response. Our findings may offer potential herbs for the topical application treatment of AD. Hindawi Publishing Corporation 2014 2014-06-15 /pmc/articles/PMC4082915/ /pubmed/25024511 http://dx.doi.org/10.1155/2014/752103 Text en Copyright © 2014 Younghee Yun et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Yun, Younghee Kim, Kyuseok Choi, Inhwa Ko, Seong-Gyu
spellingShingle	Yun, Younghee Kim, Kyuseok Choi, Inhwa Ko, Seong-Gyu Topical Herbal Application in the Management of Atopic Dermatitis: A Review of Animal Studies
author_facet	Yun, Younghee Kim, Kyuseok Choi, Inhwa Ko, Seong-Gyu
author_sort	Yun, Younghee
title	Topical Herbal Application in the Management of Atopic Dermatitis: A Review of Animal Studies
title_short	Topical Herbal Application in the Management of Atopic Dermatitis: A Review of Animal Studies
title_full	Topical Herbal Application in the Management of Atopic Dermatitis: A Review of Animal Studies
title_fullStr	Topical Herbal Application in the Management of Atopic Dermatitis: A Review of Animal Studies
title_full_unstemmed	Topical Herbal Application in the Management of Atopic Dermatitis: A Review of Animal Studies
title_sort	topical herbal application in the management of atopic dermatitis: a review of animal studies
description	Herbs are widely used in the treatment of atopic dermatitis (AD) in Eastern Asian countries, and certain herbs regarded have anti-inflammatory properties that can help with AD. With the goal of developing a topical herbal agent for AD, we conducted a systematic review of in vivo studies of AD-like skin models for screening potential herbs. Searches were conducted from PubMed and EMBASE. After all, 22 studies were included for this review. We judged most of the domains of all studies to be at unclear risk of bias. Among 22 included studies, 21 herbs have been reported to reduce AD-like skin lesions in mouse models by suppressing Th2 cell response. Our findings may offer potential herbs for the topical application treatment of AD.
publisher	Hindawi Publishing Corporation
publishDate	2014
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082915/
_version_	1613108578611101696

Topical Herbal Application in the Management of Atopic Dermatitis: A Review of Animal Studies

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