Insulin Blocks Glutamate-Induced Neurotoxicity in Differentiated SH-SY5Y Neuronal Cells

Insulin is a cytokine which promotes cell growth. Recently, a few published reports on insulin in different cell lines support the antiapoptotic effect of insulin. But the reports fail to explain the role of insulin in modulating glutamate-mediated neuronal cell death through excitotoxicity. Thus, w...

Full description

Bibliographic Details
Main Authors: Nampoothiri, Madhavan, Reddy, Neetinkumar D., John, Jessy, Kumar, Nitesh, Kutty Nampurath, Gopalan, Rao Chamallamudi, Mallikarjuna
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082871/